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  1. 26.
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    http://vocaroo.com/i/s0Wu6VtrROEh
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    #135184898 şikayet
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    http://imgim.com/55.jpg
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  3. 28.
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    holly micheals
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  4. 29.
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    #135183628 şikayet
  5. 30.
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    Prader-Willi Sendromu
    Prader-Willi Sendromu (kısaltılmış pws) hangi Kromozom 15 yedi genler (veya bunların bazı alt) ekgib veya baba tarafından kromozom üzerinde (kromozom 15q kısmi silme) unexpressed bir çok nadir genetik bozukluğu olduğunu. Andrea Prader, Heinrich Willi, Alexis Labhart, Andrew Ziegler ve Guido Fanconi isviçre tarafından 1956 yılında ilk tanımlanmıştır. pws insidansı 1 içinde 10.000 ve 1'de 15.000 canlı Doğum arasında olduğunu. Kromozom tarafından babaannesi ise köken ayrımı imprinting nedeniyle ve pws var kardeş maternally etkiler Sendromu Angelman Sendromu baskılı bölgedeki genler.

    Prader-Willi Sendromu Tanı
    pws yaklaşık 1 inç 10.000 için 1'de 15.000 Yenidoğan etkiler. pws ile dünyanın her yerinde yaşayan 400. 000'den fazla kişi vardır. Hipotoni, kısa Boy, polyphagia, obezite, küçük eller ve ayaklar, Hipogonadizm ve hafif zeka geriliği ile karakterizedir. Bu sözde pws/as bölge oluşan, örneklerin çoğunda Yağış mutasyon birkaç genetik mekanizmaları tarafından kaybolabilir. Az rastlanan diğer mekanizmaları şunlardır; uniparental disomy, sporadik mutasyonlar, kromozom translokasyonlar ve Gen silme. imprinting nedeniyle, bu genlerin maternally devralınan kopyalarını neredeyse sessiz, sadece baba tarafından kopya genlerin ifade edilir. pws babaannesi ise bu bölge kopyalarını kaybından kaynaklanır. Annenin kromozom üzerinde aynı bölgenin silinmesi Angelman Sendromu (as) neden olur. pws ve as imprinting bozuklukları insanlarda ilk rapor örnekleri gösterir.

    pws sahip etkilenen bir çocuk kardeş riski bozukluk nedeni genetik mekanizma bağlıdır. Kardeşleri için riski < etkilenen çocuğun imprinting bir mutasyon varsa etkilenen çocuğun bir genin silinmesine ya da uniparental disomy, en fazla % 50 varsa % 1 kontrol bölgesi ve yukarı bir ebeveyn kromozomal translocation ise % 25'e sunmak. Prenatal test herhangi bir bilinen genetik mekanizmaları için mümkündür.

    Çalışmalar insan ve fare modeli sistemleri c/d kutusu snoRNA SNORD116 29 kopyalarını silme (HBII-85) Prader-Willi Sendromu birincil nedeni olarak gösterilen göstermiştir.

    Prader-Willi Sendromu nöro-bilişsel
    pws
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    #135183551 şikayet
  6. 31.
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    Bu sabah, sırf kendimi zengin bir holding sahibi olarak hissedeyim diye, kahvaltıda portakal suyundan bir yudum alıp evden hızlıca çıktım..
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    #135181746 şikayet
  7. 32.
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    Office of Scholarships
    Phone: 617 747-8681
    Email Scholarships: scholarships@berklee.edu
    Email Student Employment: studentemployment@berklee.edu
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    #135181289 şikayet
  8. 33.
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    Busty MILF wants a Young Boy
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    #135180959 şikayet
  9. 34.
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    her şeyi anlarımda, camide chek-in yapmak nedir be amk barzosu ?-
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    #135180709 şikayet
  10. 35.
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    http://inci.ca/ujct26b7pm
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    #135180167 şikayet
  11. 36.
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    sevgi
    çılgın antiloplara bu okyanus
    sevgi
    zil zurna sarhoş yıldıza
    gözümü çivileyen bu göz
    sevgi
    bize benzeyen tukanların
    uyudukları bu valiz
    sevgi
    kendi dizleri altında sürgün olmaya
    karşı çıkan bu güneş
    sevgi unutuş
    ve mandalina belleğimizi
    kemiren bu aç sözcükler

    Alain BOSQUET

    Çeviri: Aytekin KARAÇOBAN

    Edit : vay amk
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    #135180127 şikayet
  12. 37.
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    Genel içerik
    , Aramıza Yeni Katılanlar(THT), E-Book, Eğlence - Geyik, Fotoğraflar, Genel Youtube Videoları, Kriptografi - Şifreleme, Oyun Haberleri, Oyun Hileleri, Serial ve Crack, Teröre Lanet, THT Yardım Merkezi, Ödev bölümü
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    #135178587 şikayet
  13. 38.
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    http://bizzarrobazar.file...ce-with-one-gal.jpg?w=640
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    #135178546 şikayet
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    #135176898 şikayet
  15. 40.
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    Sorry for my delay with reply, all tabs are contributed by users. So errors and incomplete versions are possible.
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    #135176776 şikayet
  16. 41.
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    http://www.dizimag1.com/
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  17. 42.
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    http://www.youtube.com/watch?v=CZHKoafo8UE
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    #135176752 şikayet
  18. 43.
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    I'm friends with the monster
    That's under my bed
    Get along with the voices inside of my head
    You're trying to save me
    Stop holding your breath
    And you think I'm crazy
    Yeah, you think I'm crazy (crazy)

    [Eminem - Verse 1]
    I wanted the fame, but not the cover of Newsweek
    Oh well, guess beggers can't be choosey
    Wanted to receive attention for my music
    Wanted to be left alone in public excuse me
    Been wanting my cake, And eat it too
    And wanting it both ways
    Fame made me a balloon cause my ego inflated
    When I blew seep and it was confusing
    Cause all I wanted to do is be the Bruce Lee of loose leaf
    Abused ink, used it as a tool when I blew steam
    Hit the lottery (oh wee)
    With what I gave up to get was bittersweet
    It was like winning a huge meet
    Ironic 'cause I think I'm getting so huge I need a shrink
    I'm beginning to lose sleep: one sheep, two sheep
    Going cuckoo and cookey as Kool Keith
    But I'm actually weirder than you think
    Cause I'm...

    [Chorus]
    I'm friends with the monster
    That's under my bed
    Get along with the voices inside of my head
    You're trying to save me
    Stop holding your breath
    And you think I'm crazy
    Yeah, you think I'm crazy

    Well, that's nothing
    oh oh oh oh
    Well, that's nothing
    oh oh oh oh

    [Eminem - Verse 2]
    Now I ain't much of a poet
    But I know somebody once told me to seize the moment
    And don't squander it
    Cause you never know when it could all be over
    Tomorrow so I keep conjuring
    Sometimes I wonder where these thoughts spawn from
    (Yeah, ponder it, do you want this? there's no wonder you're losing your mind the way you're wandering?)
    I think you've been wandering off down yonder and stumbled onto Jeff VanVonderen
    Cause I needed an interventionist to intervene between me and this monster
    And save me from myself and all this conflict
    Cause the very thing that I love is killing me and I can't conquer it
    My OCD is conking me in the head
    Keep knocking, nobody's home, I'm sleepwalking
    I'm just relaying what the voice in my head saying
    Don't shoot the messenger, I'm just friends with the...

    [Chorus]
    I'm friends with the monster
    That's under my bed
    Get along with the voices inside of my head
    You're trying to save me
    Stop holding your breath
    And you think I'm crazy
    Yeah, you think I'm crazy

    Well, that's nothing
    oh oh oh oh
    Well, that's nothing
    oh oh oh oh

    [Eminem - Verse 3]
    Call me crazy, but I had this vision
    One day that, I'd walk amongst you a regular civilian
    But, until then,
    drums get killed and I'm Coming straight at
    Emcees, blood get spilled and I
    Take it back to the days that, I get on a Dre track
    Give every kid who got played at
    Pumped the feeling
    and shit to say back
    To the kids who played 'em
    I ain't here to save the fucking children
    But if one kid out of a hundred million
    Who are going through a struggle feels and it relates that's great
    It's payback, Russell Wilson falling way back
    In the draft, turn nothing into something still, can make that
    Straw in the gold chump I will spend
    Rumpelstiltskin in a hay stack
    Maybe I need a straightjacket, face facts
    I am nuts for real, but I'm okay with that
    It's nothing, I'm still friends with the...

    [Bridge]
    I'm friends with the monster
    That's under my bed
    Get along with the voices inside of my head
    You're trying to save me
    Stop holding your breath
    And you think I'm crazy
    Yeah, you think I'm crazy

    I'm friends with the monster
    That's under my bed
    (Get along with)
    Get along with the voices inside of my head
    (You're tryna)
    You're trying to save me
    Stop holding your breath
    And you think I'm crazy
    Yeah, you think I'm crazy

    Well, that's nothing

    Read more: Eminem - The Monster Lyrics | MetroLyrics
    Tümünü Göster
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    http://www.youtube.com/watch?v=E94q4Txn4e8
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    http://imgim.com/1592incio5191235.jpg
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    #135176713 şikayet